microRNA target identification by transcriptomics

miRNAtarget 2.0

(Release date: 2022-04-06)

miRNAtarget is a software tool under continuous development for the analysis of the targets of differentially expressed miRNAs.

To perform miRNA-target analyses please signup. Up to twenty (20) miRNAtarget analyses is free of charge for research use. For more than twenty (20) miRNAtarget analyses for research use and for commercial use please inquire about pricing at businessdevelopment @pharmahungary.com.

miRNA-target analysis Previous analyses

Papers published so far on the utilization and validation of the miRNAtarget software

Our team published several scientific papers on the utilization and experimental validation of the predictions assessed by the miRNAtarget software. The 3 most recent publications on miRNAtarget:

Bereczki Z, Benczik B, Balogh OM, Marton Sz, Puhl E, Pétervári M, Váczy-Földi M, Papp ZsT, Makkos A, Glass K, Locquet F, Euler G, Schulz R, Ferdinandy P, Ágg B
Mitigating off-target effects of small RNAs: conventional approaches, network theory and artificial intelligence.
Br J Pharmacol. 2024 Sep 18;182(2):340-379
Szabados T, Makkos A, Ágg B, Benczik B, Brenner GG, Szabó M, Váradi B, Vörös I, Gömöri K, Varga ZV, Görbe A, Bencsik P, Ferdinandy P
Pharmacokinetics and cardioprotective efficacy of intravenous miR-125b* microRNA mimic in a mouse model of acute myocardial infarction.
Br J Pharmacol. 2024 Oct 29;182(2):432–450.
Nagy RN, Makkos A, Baranyai T, Giricz Z, Szabó M, Kravcsenko-Kiss B, Bereczki Z, Ágg B, Puskás LG, Faragó N, Schulz R, Gyöngyösi M, Lukovic D, Varga Z V, Görbe A, Ferdinandy P
Cardioprotective microRNAs (protectomiRs) in a pig model of acute myocardial infarction and cardioprotection by ischaemic conditioning: MiR-450a.
Br J Pharmacol. 2024 Sep 18;182(2):396-432.

Complete list of research articles on miRNAtarget ...

Developed by

miRNAtarget was developed in the collaboration of the Pharmahungary Group and the Department of Pharmacology and Pharmacotherapy, Semmelweis University.

Supported by

This study was supported by the National Research, Development and Innovation Office of Hungary (NKFIA; National Heart Program NVKP-16-1-2016-0017). The research was financed by the Thematic Excellence Programme (2020-4.1.1.-TKP2020) of the Ministry for Innovation and Technology in Hungary, within the framework of the Therapeutic Development and Bioimaging thematic programmes of the Semmelweis University. Project no. RRF-2.3.1-21-2022-00003 has been implemented with the support provided by the European Union.

Contact

If you need technical support please contact
[email protected].

Terms and Conditions

Please read Terms and Conditions of the miRNAtarget service.

miRNAtarget 2.0 features

(release date: 2022-04-06)

Aims

to analyze the targets of miRNAs from a network theoretical perspective
to predict the most probable targets of differentially expressed miRNAs

Advantages

miRNAtarget relies on multiple miRNA-target interaction databases
simple and powerful network theoretical approach to identify the most probable targets of differentially expressed miRNAs
increased coverage of possible miRNA-target interactions compared to experimentally validated databases
higher accuracy than available predicted miRNA-target interaction databases
intuitive relative entropy optimization-based network visualization
interactions predicted by miRNAtarget has been successfully validated in multiple animal studies

Recommended for

basic researchers
small biotech companies
pharmaceutical industry